Sodium Hydroxide → HCID 67337738, compound

Participants

Reaction Conditions

Reaction Steps

To the solution prepared in step c was added 6 N NaOH (6 mL), and the resulting mixture was heated to 60° C. overnight. The reaction mixture was cooled to room temperature, and purified directly (without concentrating or work up) using reverse-phase HPLC (Phenomenex, 2-15% CH3CN/H2O, 0.1% TFA, 6 min) to afford 0.95 g (50%) of the title compound. MS (ES+): m/e 351.1 [M+H]+.

Provenance & Evidence