Cyanuric chloride → 2,4-Dichloro-6-methyl-1,3,5-triazine

Participants

Reaction Steps

To a THF (8 ml) solution of 2,4,6-trichloro-1,3,5-triazine (300 mg, 1.63 mmol, 1.00 equiv) at 0° C., methylmagnesium bromide (0.596 ml, 1.79 mmol, 1.10 equiv) was added. The reaction was allowed to warm to room temperature and stirring was continued overnight. The reaction was quenched by addition of water. The product was extracted with ethyl acetate; washed with sat sodium chloride; dried with sodium sulfate; filtered and concentrated under reduced pressure to afford the title compound. The crude product was carried forward. MS (ES+): m/e 186.1 [M+Na]+.

Provenance & Evidence