反应详情

5′-tert-Butoxycarbonylamino-2′-trifluoromethoxy-biphenyl-4-carboxylic acid ethyl ester (200 mg) in ethanol (7 ml) and 2M sodium hydroxide (4 ml) was stirred at 20 C for 18 h. The ethanol was then evaporated and the residue acidified. The solid thus formed was collected by filtration and dried (128 mg)

1. customThe ethanol was then evaporated
2. customThe solid thus formed
3. filtrationwas collected by filtration
4. customdried (128 mg)