HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylmorpholine → HCID 16382960, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylmorpholine | HCID 7972 | — |
| Reactant | 1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide | HCID 15908 | — |
| Reactant | 3-Bromo-4-methoxybenzoic acid | HCID 66836 | — |
| Reactant | Benzenamine, 4-(4-morpholinyl)- | HCID 75655 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 16382960 | HCID 16382960 | — |
Reaction Steps
A mixture of 3-bromo-4-methoxy-benzoic acid (500 mg), N-(4-aminophenyl)morpholine (385 mg), EDAC (828 mg), HOBT (583 mg) and N-methylmorpholine (714 μl) in DMF (5 ml) was stirred at room temperature for 18 h. The mixture was then diluted with water (30 ml) and the resulting solid collected by filtration and dried (818 mg)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08008303B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-bb673868e5d54683bb0b3e8c3ae45949 |
| Source note | uspto-grants-2011_08 |