HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylmorpholine → HCID 131729132, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylmorpholine | HCID 7972 | — |
| Reactant | 1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide | HCID 15908 | — |
| Reactant | 3-Bromo-4-methoxybenzoic acid | HCID 66836 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | 4-(4-Aminobenzyl)thiomorpholine 1,1-dioxide | HCID 2779682 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 131729132 | HCID 131729132 | — |
Reaction Steps
A mixture of 3-bromo-4-methoxy-benzoic acid (500 mg), 4-(1,1-dioxo-1lambda*6*-thiomorpholin-4-ylmethyl)-phenylamine (519 mg), EDAC (830 mg), HOBT (585 mg) and N-methylmorpholine (712 μl) in DMF (3 ml) was stirred at room temperature for 18 h. The mixture was then diluted with water (30 ml) and the resulting solid collected by filtration and dried (882 mg)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08008303B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-beb8418feba54d3fae4055945b62a02b |
| Source note | uspto-grants-2011_08 |