Hydrochloric Acid → HCID 19705952, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of methyl 4-(2-phenylethoxy)benzenepropanoate (0.65 g, 2.3 mmol) in methanol (3 mL) was added a 2 N aqueous sodium hydroxide solution (3 mL), and the mixture was stirred at 50° C. for 1 hour. To the reaction solution was added 2 N hydrochloric acid (2.5 mL), and extracted with ethyl acetate. The extract was washed with water, and then concentrated under reduced pressure. The residue was recrystallized from ethyl acetate-hexane to give the title compound (0.50 g, yield 81%).

Provenance & Evidence