N-bromobutanimide → HCID 23136352, compound

Participants

Reaction Conditions

Reaction Steps

1-(3-Methylphenoxy)naphthalene (500 mg, 2.1 mmol) was dissolved in benzotrifluoride (30 mL), N-bromosuccinimide (417 mg, 2.3 mmol) and 2,2′-azobis(isobutyronitrile) (10 mg, 0.06 mmol) were added thereto, and then the mixture was stirred at 100° C. for 4 hours. The reaction solution was filtered, and concentrated under reduced pressure. The residue was purified with silica gel column chromatography (hexane/ethyl acetate=100:0 to 90:10) to give the title compound (481 mg, yield 73%).

Provenance & Evidence