HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 178523810, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | [2-(4-Chloro-phenyl)-2H-indazol-3-yl]-cyclohexyl-acetic acid | HCID 67131005 | — |
| Reactant | HCID 178511715 | HCID 178511715 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Product | HCID 178523810 | HCID 178523810 | — |
Reaction Steps
In analogy to the procedure described in example 6, [2-(4-chloro-phenyl)-2H-indazol-3-yl]-cyclohexyl-acetic acid was converted into the corresponding acid chloride with thionyl chloride which subsequently reacted with (trans)-4-amino-cyclohexanol (CAS Reg. No. 27489-62-9) in the presence of DMAP to give the title compound as colorless oil. MS: m/e=466.4 [M+H+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08008505B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-52dee1fab48c4195a27ad1e9cfdf7d51 |
| Source note | uspto-grants-2011_08 |