HCID 67130964, compound → HCID 67131172, compound

HRID 1678643Notes

Reaction equation

HRID 1678643 reaction equation
[C:1]([O:5][C:6]([C:8]1([O:11][C:12]2[CH:17]=[CH:16][C:15]([N+:18]([O-])=O)=[C:14]([F:21])[CH:13]=2)[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2]>[Pd].C(O)C>[C:1]([O:5][C:6]([C:8]1([O:11][C:12]2[CH:17]=[CH:16][C:15]([NH2:18])=[C:14]([F:21])[CH:13]=2)[CH2:9][CH2:10]1)=[O:7])([CH3:4])([CH3:2])[CH3:3]

Participants

4

Reactant 1

HCID 67130964HCID 67130964, compound

Product 1

HCID 67131172HCID 67131172, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

In analogy to the procedure described in example 15.2, 1-(3-fluoro-4-nitro-phenoxy)-cyclopropanecarboxylic acid tert-butyl ester was hydrogenated in the presence of 10% palladium on charcoal in ethanol to give the title compound as brown solid. MS: m/e=268.2 [M+H+].

Sources & evidence

ORD record
ord-7a2e2ce94b8f4cb18ac2ce6d53869a39
Source dataset
uspto-grants-2011_08
Patent number
US08008505B2

Reaction notes

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