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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1678660Generated: October 30, 2026

Lithium Hydroxide → HCID 45110921, compound

https://huagongshe.com/reaction/1678660

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
ReactantHCID 67131198HCID 67131198—
SolventMethanolHCID 887—
SolventTetrahydrofuranHCID 8028—
ProductHCID 45110921HCID 45110921—

Reaction Steps

In analogy to the procedure described in example 7.2, [rac]-4-{2-[2-(4-chloro-phenyl)-2H-indazol-3-yl]-2-cyclohexyl-ethoxy}-3,5-dimethyl-benzoic acid methyl ester was treated with 1 N aqueous lithium hydroxide solution in THF and MeOH to give the title compound as colorless foam. MS: m/e=503.2 [M+H+].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08008505B2
Source datasetuspto-grants-2011_08
ORD IDord-26cc615484ef48a1b6b59ab72cbf5335
Source noteuspto-grants-2011_08