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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1678676Generated: November 2, 2026

Lithium Hydroxide → HCID 45111662, compound

https://huagongshe.com/reaction/1678676

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
ReactantHCID 67131073HCID 67131073—
SolventMethanolHCID 887—
SolventTetrahydrofuranHCID 8028—
ProductHCID 45111662HCID 45111662—

Reaction Steps

In analogy to the procedure described in example 7.2, [rac]-6-{2-[2-(4-chloro-phenyl)-2H-indazol-3-yl]-2-cyclohexyl-ethoxy}-nicotinic acid methyl ester was treated with 1 N aqueous lithium hydroxide solution in THF and MeOH to give the title compound as colorless oil. MS: m/e=476.1 [M+H+].

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08008505B2
Source datasetuspto-grants-2011_08
ORD IDord-564f32fec65a4ecc9a7848fd7ca35b73
Source noteuspto-grants-2011_08