alpha-Chloro-o-xylene → HCID 20364913, compound

Participants

Reaction Steps

Using the procedure of Example 9, 5-hydroxy-2-(3-chlorophenyl)-1,3-dioxane (21.5 g, 0.1 mole) was reacted with 2-methylbenzyl chloride (14.0 g, 0.1 mole) to give a heavy oil, which on distillation under 1 × 10-4 mm pressure gave 12.5 g of product which distilled at a pot temperature of 160°-170° C. Analysis by nmr indicated this product to contain 18% cis-5-(2-methylbenzyloxy)-2-(3-chlorophenyl)-1,3-dioxane.

Provenance & Evidence