HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Phenylmethoxy)-1,3-propanediol → 5-Benzyloxy-2-(3-chlorophenoxymethyl)-1,3-dioxane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Phenylmethoxy)-1,3-propanediol | HCID 203567 | — |
| Reactant | 1-Chloro-3-(2,2-diethoxyethoxy)benzene | HCID 12661796 | — |
| Product | 5-Benzyloxy-2-(3-chlorophenoxymethyl)-1,3-dioxane | HCID 20365012 | — |
Reaction Steps
Using the procedure of Example 47, (3-chlorophenoxy)acetaldehyde diethyl acetal and 2-benzyloxy-1,3-propanediol were reacted to give 5-benzyloxy-2-(3-chlorophenoxymethyl)-1,3-dioxane, nD25 1.5587. The ir spectrum was consistent with the assigned structure. The nmr spectrum indicated 40% cis isomer and 60% trans isomer.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04077982 |
| Source dataset | uspto-grants-1978_03 |
| ORD ID | ord-6fd987861c4740498dc06d37b72401ac |
| Source note | uspto-grants-1978_03 |