Acetaldehyde → HCID 20364868, compound

HRID 1679019Notes

Reaction equation

HRID 1679019 reaction equation
[F:1][C:2]1[CH:15]=[CH:14][CH:13]=[CH:12][C:3]=1[CH2:4][O:5][C:6]([CH3:11])([CH2:9][OH:10])[CH2:7][OH:8].[CH:16](=O)[CH3:17]>CCCCCC>[F:1][C:2]1[CH:15]=[CH:14][CH:13]=[CH:12][C:3]=1[CH2:4][O:5][C:6]1([CH3:11])[CH2:9][O:10][CH:16]([CH3:17])[O:8][CH2:7]1

Participants

4

Reactant 2

HCID 177AcetaldehydeHCID 20364943HCID 20364943, compound

Product 1

HCID 20364868HCID 20364868, compound

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

Using the procedure of Example 51, 2-(2-fluorobenzyloxy)-2-methyl-1,3-propanediol and acetaldehyde were reacted, using hexane as solvent to give, after separation by column chromatography, t-5-(2-fluorobenzyloxy)-r-2-methyl-5-methyl-1,3-dioxane, nD25 1.4902, and c-5-(2-fluorobenzyloxy)-r-2-methyl-5-methyl-1,3-dioxane, nD25 1.4939. The ir and nmr spectra were consistent with the assigned structures.

Workup

  1. customwere reacted
  2. customto give
  3. customafter separation by column chromatography, t-5-(2-fluorobenzyloxy)-r-2-methyl-5-methyl-1,3-dioxane

Sources & evidence

ORD record
ord-bd6ee057fc624756aed7b0cf290f7667
Source dataset
uspto-grants-1978_03
Patent number
US04077982

Reaction notes

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