Pentanal → HCID 20364882, compound

HRID 1679026Notes

Reaction equation

HRID 1679026 reaction equation
[F:1][C:2]1[CH:15]=[CH:14][CH:13]=[CH:12][C:3]=1[CH2:4][O:5][C:6]([CH3:11])([CH2:9][OH:10])[CH2:7][OH:8].[CH:16](=O)[CH2:17][CH2:18][CH2:19][CH3:20]>C1C=CC=CC=1>[CH2:17]([CH:16]1[O:10][CH2:9][C:6]([O:5][CH2:4][C:3]2[CH:12]=[CH:13][CH:14]=[CH:15][C:2]=2[F:1])([CH3:11])[CH2:7][O:8]1)[CH2:18][CH2:19][CH3:20]

Participants

4

Reactant 2

HCID 8063PentanalHCID 20364943HCID 20364943, compound

Product 1

HCID 20364882HCID 20364882, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

Using the procedure of Example 51, 2-(2-fluorobenzyloxy)-2-methyl-1,3-propanediol and valeraldehyde were reacted, using benzene as solvent, to give, after separation by column chromatography, r-2-butyl-t-5-(2-fluorobenzyloxy)-5-methyl-1,3-dioxane, b.p. 105°/0.05 mm, nD25 1.4840; and r-2-butyl-c-5-(2-fluorobenzyloxy)-5-methyl-1,3-dioxane, b.p. 105°/0.025 mm, nD25 1.4865. The ir and nmr spectra were consistent with the assigned structures.

Workup

  1. customwere reacted
  2. customto give
  3. customafter separation by column chromatography, r-2-butyl-t-5-(2-fluorobenzyloxy)-5-methyl-1,3-dioxane, b.p. 105°/0.05 mm

Sources & evidence

ORD record
ord-5dcf825ae3d543c2b1139ad406930982
Source dataset
uspto-grants-1978_03
Patent number
US04077982

Reaction notes

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