Cyclohexanone → HCID 20364911, compound

HRID 1679028Notes

Reaction equation

HRID 1679028 reaction equation
[C:1]1(=[O:7])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[F:8][C:9]1[CH:22]=[CH:21][CH:20]=[CH:19][C:10]=1[CH2:11][O:12][C:13]([CH3:18])([CH2:16]O)[CH2:14][OH:15]>C1C=CC=CC=1>[F:8][C:9]1[CH:22]=[CH:21][CH:20]=[CH:19][C:10]=1[CH2:11][O:12][C:13]1([CH3:18])[CH2:14][O:15][C:1]2([CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]2)[O:7][CH2:16]1

Participants

4

Reactant 2

HCID 7967CyclohexanoneHCID 20364943HCID 20364943, compound

Product 1

HCID 20364911HCID 20364911, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

Using the procedure of Example 51, cyclohexanone and 2-(2-fluorobenzyloxy)-2-methyl-1,3-propanediol were reacted, using benzene as solvent, to give 3-(2-fluorobenzyloxy)-3-methyl-1,5-dioxaspiro[5.5]undecane, b.p. 170°-174°/0.03 mm, nD25 1.5081. The ir and nmr spectra were consistent with the assigned structure.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-d7271f3aec4449788dfccd65980f5e36
Source dataset
uspto-grants-1978_03
Patent number
US04077982

Reaction notes

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