o-Benzoyl-p-chloro-phenylglyoxylic acid ethyl ester → Ethyl 5-chloro-3-phenyl-2-benzofuran-1-carboxylate

HRID 1679072Notes

Reaction equation

HRID 1679072 reaction equation
[CH2:1]([O:3][C:4](=[O:22])[C:5]([C:7]1[CH:12]=[CH:11][C:10]([Cl:13])=[CH:9][C:8]=1[C:14](=[O:21])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)=O)[CH3:2]>C(Cl)Cl>[CH2:1]([O:3][C:4]([C:5]1[O:21][C:14]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[C:8]2[C:7]=1[CH:12]=[CH:11][C:10]([Cl:13])=[CH:9]2)=[O:22])[CH3:2]

Participants

3

Reactant 1

HCID 54162441o-Benzoyl-p-chloro-phenylglyoxylic acid ethyl ester

Product 1

HCID 54496268Ethyl 5-chloro-3-phenyl-2-benzofuran-1-carboxylate

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

o-benzoyl-p-chloro-phenylglyoxylic acid ethyl ester as a light-yellow thick oil after chromatography on silica gel with methylene chloride as the eluant.

Sources & evidence

ORD record
ord-8138beabe8f7421c99d8573fa2e8f556
Source dataset
uspto-grants-1978_03
Patent number
US04077978

Reaction notes

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