Acetic Acid → HCID 178468986, compound

HRID 1679100Notes

Reaction equation

HRID 1679100 reaction equation
[CH2:1]([O:3][C:4](=[O:12])[C:5]1[CH:10]=[CH:9][C:8]([NH2:11])=[CH:7][CH:6]=1)[CH3:2].[CH2:13]([N+:17]([O-])=O)/[CH:14]=[N:15]\[OH:16].C(O)(=[O:22])C>>[C:4]([C:5]1[CH:10]=[CH:9][C:8]([N:11]2[N:17]=[C:13]([OH:22])[CH:14]=[N+:15]2[O-:16])=[CH:7][CH:6]=1)([O:3][CH2:1][CH3:2])=[O:12]

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 2337BenzocaineHCID 58810166(NZ)-N-(2-nitroethylidene)hydroxylamine

Product 1

HCID 178468986HCID 178468986, compound

Procedure

280 g of oxime-hydrazone II (R = carbethoxyphenyl), prepared from diazotised 4-aminobenzoic acid-ethyl ester and methazonic acid, is stirred in 2000 ml of acetic acid for 10 hours at 60° C. The whole is cooled and the precipitate is filtered off with suction, well washed with water and again filtered off with suction.

Workup

  1. temperatureThe whole is cooled
  2. filtrationthe precipitate is filtered off with suction
  3. washwell washed with water
  4. filtrationagain filtered off with suction

Sources & evidence

ORD record
ord-962b3de1e0c34025a7bb14a731385d56
Source dataset
uspto-grants-1978_03
Patent number
US04079063

Reaction notes

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