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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1679110Generated: October 29, 2026

Diethyl (ethoxymethylene)malonate → HCID 86733250, compound

https://huagongshe.com/reaction/1679110

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethyl (ethoxymethylene)malonateHCID 6871—
ReactantEthyl 2-Amino-5-methylthiophene-3-carboxylateHCID 4062885—
SolventEthanolHCID 702—
ProductHCID 86733250HCID 86733250—

Reaction Conditions

Temperature110 °C

Reaction Steps

A mixture of 3.7 parts of ethyl 2-amino-5-methylthiophene-3-carboxylate and 4.4 parts of diethyl ethoxymethylenemalonate is heated at 110° C for 1.5 hour. After cooling ethanol is added and the crystals are collected by filtration, whereby diethyl (3-ethoxycarbonyl-5-methylthienyl)aminomethylenemalonate is obtained as crystals. Recrystallization from ethanol gives pale yellow needles melting at 67°-68° C

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04079060
Source datasetuspto-grants-1978_03
ORD IDord-75cf9c0ecb954d29999e8a5a27baa276
Source noteuspto-grants-1978_03