Nitric Acid → HCID 54221367, compound

Participants

Reaction Steps

To 166 ml. of acetic anhydride were dropped 27.7 g. 20% nitric acid at 25° C. under ice cooling over a 45 minute period. This was followed by the hour long addition of 19.5 g. of 1,3-cyclo hexadiene at 25° C. (ice cooling from time to time). After an additional hour stirring the reaction was poured onto ice and worked up as above. Purification over silicagel yielded acetic acid (4-nitro-cyclohex-2-en-1-yl)ester as a cis/trans mixture.

Provenance & Evidence