Acetic Anhydride → HCID 54347407, compound

HRID 1679164Notes

Reaction equation

HRID 1679164 reaction equation
[C:1]1([C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[CH:6]=[CH:5][C:4]([C:7]([C:11]2[CH:16]=[CH:15][C:14]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)=[CH:13][CH:12]=2)=[CH:8][CH2:9][NH2:10])=[CH:3][CH:2]=1.[C:29](OC(=O)C)(=[O:31])[CH3:30]>C(O)(=O)C>[C:14]1([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH:15]=[CH:16][C:11]([C:7]([C:4]2[CH:3]=[CH:2][C:1]([C:23]3[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=3)=[CH:6][CH:5]=2)=[CH:8][CH2:9][NH:10][C:29](=[O:31])[CH3:30])=[CH:12][CH:13]=1

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 20363851HCID 20363851, compound2×

Product 1

HCID 54347407HCID 54347407, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

1, 1-di(4-biphenyl)-3 (1g) was added to a mixture of anhydrous sodium acetate (1g), acetic acid (10 ml.) and acetic anhydride (1 ml) and the mixture was refluxed for 1 hour then evaporated in vacuo. The residue was washed with water and dried and recrystallised from n- propanol to give 1, 1-di(4-biphenylyl)- 3 -acetamido-prop-1-ene. (m.p. 246° - 249° C). This compound was reduced in a similar manner to the method described in Example 43 to yield 1,1-di(4-biphenyly;0- 3 -ethylamino-prop-1-ene.

Workup

  1. temperaturethe mixture was refluxed for 1 hour
  2. customthen evaporated in vacuo
  3. washThe residue was washed with water
  4. customdried
  5. customrecrystallised from n- propanol

Sources & evidence

ORD record
ord-9905db60d81c421882c2fe919846040a
Source dataset
uspto-grants-1978_03
Patent number
US04079081

Reaction notes

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