HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → N-[4-(Benzylsulfanyl)-2-nitrophenyl]acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | Thiocyanic acid, 4-(acetylamino)-3-nitrophenyl ester | HCID 8180927 | — |
| Solvent | Water | HCID 962 | — |
| Product | N-[4-(Benzylsulfanyl)-2-nitrophenyl]acetamide | HCID 20362823 | — |
Reaction Steps
2.37 G. 1-acetamido-2-nitro-4-thiocyanatobenzene in 10 ml. dimethylformamide under nitrogen is treated with 0.38 g. sodium borohydride at 20°-25° C. After one hour 2.4 ml. benzylbromide is added, the mixture left for 2 hours, then diluted with water, filtered, washed with cyclohexane, recrystallized from methanol yielding 1-acetamido-2-nitro-4-benzylthiobenzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04080461 |
| Source dataset | uspto-grants-1978_03 |
| ORD ID | ord-85293db323a14b739ca39a336ec8f75e |
| Source note | uspto-grants-1978_03 |