反应详情

6.4 G. of 1-amino-2-nitro-4-(2-ethoxyethylthio) benzene in 100 ml. of methanol and 50 ml. of water is treated with 16 ml. of sodium dithionite and 14 g. sodium carbonate at reflux under nitrogen. Heating is continued for one-half hour, then the methanol is evaporated from the mixture. The mixture is diluted with 100 ml. of water and is extracted with chloroform. The chloroform solution is dried over sodium sulfate and 1,2-diamino-4-(2-ethoxyethylthio) benzene is obtained by evaporation of the solution.

1. temperatureHeating
2. waitis continued for one-half hour
3. customthe methanol is evaporated from the mixture
4. additionThe mixture is diluted with 100 ml
5. extractionof water and is extracted with chloroform
6. dry with materialThe chloroform solution is dried over sodium sulfate