反应详情

4.5 Kg. of 1-amino-2-nitro-5-phenylthiobenzene in 60 l. of methanol and 30 l. of water is treated, under nitrogen, with 8.0 kg. of sodium dithionite and 2.0 kg. of sodium carbonate at reflux. The mixture is heated for 2 hours and the methanol is removed by distillation. The mixture is cooled and extracted with dichloromethane. The dichloromethane solution is filtered, dried over sodium sulfate, and 1,2-diamino-4-phenylthiobenzene is isolated by evaporation.

1. temperatureThe mixture is heated for 2 hours
2. customthe methanol is removed by distillation
3. temperatureThe mixture is cooled
4. extractionextracted with dichloromethane
5. filtrationThe dichloromethane solution is filtered
6. dry with materialdried over sodium sulfate