Bromine → HCID 20363010, compound

HRID 1679490Notes

Reaction equation

HRID 1679490 reaction equation
[O:1]=[C:2]1[N:7]([CH3:8])[C:6](=[O:9])[N:5]([CH2:10][CH3:11])[CH2:4][N:3]1[CH2:12][CH3:13].[Br:14]Br>C(Cl)Cl>[Br-:14].[O:1]=[C:2]1[N:7]([CH3:8])[C:6](=[O:9])[N:5]([CH2:10][CH3:11])[CH2:4][NH+:3]1[CH2:12][CH3:13]

Participants

4

Reactant 2

HCID 24408BromineHCID 12397333HCID 12397333, compound

Product 1

HCID 20363010HCID 20363010, compoundYield 87%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

18.5 g (0.1 mol) of 2,4-dioxo-hexahydro-1,5-diethyl-3-methyl-s-triazine are dissolved in 20 ml of methylene chloride and 24 g (0.15 mol) of bromine are added dropwise. The temperature is kept at 20° C to 30° C by occasional cooling. After a few minutes, an orange-coloured precipitate separates out. This is filtered off and recrystallised from isopropanol. 23 g (87%) of 2,4-dioxo-1,2,3,4-tetrahydro-1,5-diethyl-3-methyl-s-triazinium bromide of melting point 198° C are obtained.

Workup

  1. customis kept at 20° C to 30° C by occasional cooling
  2. waitAfter a few minutes
  3. filtrationThis is filtered off
  4. customrecrystallised from isopropanol

Sources & evidence

ORD record
ord-ca70a67f702c406b9c18c9bbb3fae77a
Source dataset
uspto-grants-1978_03
Patent number
US04080502

Reaction notes

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