Bromine → HCID 20363005, compound

HRID 1679491Notes

Reaction equation

HRID 1679491 reaction equation
[O:1]=[C:2]1[N:7]([CH3:8])[C:6](=[O:9])[N:5]([CH:10]2[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]2)[CH2:4][N:3]1[CH:16]1[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1.[Br:22]Br>C(Cl)Cl>[Br-:22].[O:1]=[C:2]1[N:7]([CH3:8])[C:6](=[O:9])[N:5]([CH:10]2[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11]2)[CH2:4][NH+:3]1[CH:16]1[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1

Participants

4

Reactant 2

HCID 24408BromineHCID 12397335HCID 12397335, compound

Product 1

HCID 20363005HCID 20363005, compoundYield 67%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

29.3 g (0.1 mol) of 2,4-dioxo-hexahydro-1,5-dicyclohexyl-3-methyl-s-triazine are initially introduced into 40 ml of methylene chloride and 24 g (0.15 mol) of bromine are added dropwise. The temperature is kept at 20° C to 30° C by cooling. The orange-red precipitate which has separated out is filtered off and recrystallised from isopropanol. 25 g (67%) of 2,4-dioxo-1,2,3,4-tetrahydro-1,5-dicyclohexyl-3-methyl-s-triazinium bromide of melting point 250° C are obtained.

Workup

  1. additionare added dropwise
  2. customis kept at 20° C to 30° C
  3. temperatureby cooling
  4. customThe orange-red precipitate which has separated out
  5. filtrationis filtered off
  6. customrecrystallised from isopropanol

Sources & evidence

ORD record
ord-c672c62354084063909b45f5b727822e
Source dataset
uspto-grants-1978_03
Patent number
US04080502

Reaction notes

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