Bromine → HCID 20363020, compound

HRID 1679493Notes

Reaction equation

HRID 1679493 reaction equation
[O:1]=[C:2]1[N:7]([CH3:8])[C:6](=[O:9])[N:5]([CH:10]([CH3:12])[CH3:11])[CH2:4][N:3]1[CH:13]([CH3:15])[CH3:14].[Br:16]Br>C(Cl)Cl>[Br-:16].[O:1]=[C:2]1[N:7]([CH3:8])[C:6](=[O:9])[N:5]([CH:10]([CH3:11])[CH3:12])[CH2:4][NH+:3]1[CH:13]([CH3:15])[CH3:14]

Participants

4

Reactant 2

HCID 24408BromineHCID 12397334HCID 12397334, compound

Product 1

HCID 20363020HCID 20363020, compoundYield 55%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

21.3 g (0.1 mol) of 2,4-dioxo-hexahydro-1,5-diisopropyl-3-methyl-s-triazine are dissolved in 30 ml of methylene chloride and 24 g (0.15 mol) of bromine are added dropwise. The temperature is kept at 20° C to 30° C by cooling. After one hour, the orange-coloured precipitate which has formed is filtered off and recrystallised from isopropanol. 16 g (55%) of 2,4-dioxo-1,2,3,4-tetrahydro-1,5-diisopropyl-3-methyl-s-triazinium bromide are obtained as white crystals which melt at 210°-212° C.

Workup

  1. customis kept at 20° C to 30° C
  2. temperatureby cooling
  3. customthe orange-coloured precipitate which has formed
  4. filtrationis filtered off
  5. customrecrystallised from isopropanol

Sources & evidence

ORD record
ord-8afb1e4ec86940fca8c636bad09dff7e
Source dataset
uspto-grants-1978_03
Patent number
US04080502

Reaction notes

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