Pyridine → HCID 178435661, compound

HRID 1679500Notes

Reaction equation

HRID 1679500 reaction equation
[C:1]1(C)C=CC(S([O-])(=O)=O)=C[CH:2]=1.[CH2:12]([C:19]1[S:20][C:21]2[CH:29]=[CH:28][CH:27]=[CH:26][C:22]=2[N+:23]=1CC)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[C:30](OC(=O)C)(=[O:32])[CH3:31].N1C=CC=CC=1>O>[CH2:1]([C:26]1[C:22]2[NH:23][C:19](=[C:12]([C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=3)[C:30]([CH3:31])=[O:32])[S:20][C:21]=2[CH:29]=[CH:28][CH:27]=1)[CH3:2]

Participants

5

Reactant 3

HCID 1049PyridineHCID 7918Acetic AnhydrideHCID 20362957HCID 20362957, compound

Product 1

HCID 178435661HCID 178435661, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

2-Benzyl-3-ethylbenzothiazolium p-toluenesulfonate (34 g, 0.08 mol), acetic anhydride (8.9 g, 0.088 mol) and dry pyridine (100 ml) are heated at reflux for 15 min., cooled and diluted with 1 liter of water. The oil which separates becomes crystalline on stirring. It is collected on a filter and washed with water. Yield 22.8 g (97%).

Workup

  1. temperatureat reflux for 15 min.
  2. temperaturecooled
  3. customIt is collected on
  4. filtrationa filter
  5. washwashed with water

Sources & evidence

ORD record
ord-6ad98ccd259d4088ac0828877e902795
Source dataset
uspto-grants-1978_03
Patent number
US04080496

Reaction notes

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