HuagongsheHuagongshe Chemistry Print Report · For research reference only
Resorcinol → 3,4-Dihydro-7-hydroxy-4-(1-naphthyl)coumarin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Resorcinol | HCID 5054 | — |
| Reactant | 3-(1-Naphthalenyl)-2-propenoic acid | HCID 98307 | — |
| Reactant | hydrochloric acid HCl | HCID 21225539 | — |
| Product | 3,4-Dihydro-7-hydroxy-4-(1-naphthyl)coumarin | HCID 20570522 | 64% |
Reaction Steps
Condensation of resorcinol with 3-(1-naphthyl)acrylic acid in the presence of hydrochloric acid/hydrogen chloride (method of J. D. Simpson and H. Stephen, J. Chem. Soc. (London) 1936, 1382) gave the desired dihydrocoumarin, m.p. 203.5°-206.5°, in 64% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04080335 |
| Source dataset | uspto-grants-1978_03 |
| ORD ID | ord-ccb5beb5ba14436ea8cc14c0c881eaf7 |
| Source note | uspto-grants-1978_03 |