1-Chloro-2-(diethylamine)ethane hydrochloride → 7-(2-Diethylaminoethoxy)-2,2-dimethyl-4-(2-naphthyl)-2H-chromene

Participants

Role	Name	HCID	Charge
Reactant	1-Chloro-2-(diethylamine)ethane hydrochloride	HCID 13363	—
Reactant	2-((3,4-Dihydro-2,2-dimethyl-4-(4-(trifluoromethyl)phenyl)-2H-1-benzopyran-7-yl)oxy)-N,N-dimethylethanamine	HCID 42990	—
Reactant	2,2-Dimethyl-4-(naphthalen-2-yl)-2H-1-benzopyran-7-ol	HCID 20570540	—
Product	7-(2-Diethylaminoethoxy)-2,2-dimethyl-4-(2-naphthyl)-2H-chromene	HCID 20570486	49%

Reaction Steps

Reaction of 2-diethylaminoethylchloride hydrochloride with 2,2-dimethyl-4-(2-naphthyl)-2H-chromen-7-ol by an analogous method to that described in Preparation 18 (c) gave the title compound as a colourless oil in 49% yield.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US04080335
Source dataset	uspto-grants-1978_03
ORD ID	ord-3444ab1735c24faa9ab7f850fd94779b
Source note	uspto-grants-1978_03