Potassium Permanganate → HCID 135441872, compound

HRID 1679535Notes

Reaction equation

HRID 1679535 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1[NH:12][C:11](=[O:13])[CH:10]([CH3:14])[NH:9][N:8]=1.[Mn]([O-])(=O)(=O)=O.[K+]>CC(C)=O>[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1[NH:12][C:11](=[O:13])[C:10]([CH3:14])=[N:9][N:8]=1

Participants

4

Reactant 2

HCID 516875Potassium PermanganateHCID 135840399HCID 135840399, compound

Product 1

HCID 135441872HCID 135441872, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent2×

Procedure

In a 500 ml four-necked flask was charged a solution of 7.4 g of the above prepared 3-(2-pyridyl)-6-methyl-1,4,5,6-tetrahydro-1,2,4-triazin-5-one in 200 ml of acetone, and a solution of 3.2 g of potassium permanganate in 200 ml of acetone was added dropwise thereto at 10° to 15° C while stirring. The resulting mixture was stirred for 2 hours, and then the produced manganese dioxide was removed by filtration. The acetone was removed under reduced pressure to obtain 6.5 g of 3-(2-pyridyl)-6-methyl-4,5-dihydro-1,2,4-triazin-5-one as white crystals. M.P. 299°-300° C. Anal. Calcd. for C9H8N4O: C, 57.45%; H, 4.26%; N, 29.79%. Found: C, 57.31%; H, 4.22%; N, 29.95%.

Workup

  1. additionIn a 500 ml four-necked flask was charged a solution of 7.4 g of the
  2. stirringThe resulting mixture was stirred for 2 hours
  3. customthe produced manganese dioxide was removed by filtration
  4. customThe acetone was removed under reduced pressure

Sources & evidence

ORD record
ord-3d4d595260e3495584d3915b82f73459
Source dataset
uspto-grants-1978_03
Patent number
US04081267

Reaction notes

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