HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 8-methylthio-6-phenyl-1-[(phthalimidooxy)methyl]-4H-s-triazolo[4,3-a][1,4]-benzodiazepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | N-Hydroxyphthalimide | HCID 10665 | — |
| Reactant | 8-(methylthio)-1-(chloromethyl)-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine | HCID 20361160 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 8-methylthio-6-phenyl-1-[(phthalimidooxy)methyl]-4H-s-triazolo[4,3-a][1,4]-benzodiazepine | HCID 20361242 | — |
Reaction Steps
In the manner given in Example 1, N-hydroxyphthalimide and triethylamine in dimethylformamide is treated with 8-methylthio-6-phenyl-1-(chloromethyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine to give 8-methylthio-6-phenyl-1-[(phthalimidooxy)methyl]-4H-s-triazolo[4,3-a][1,4]benzodiazepine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04081452 |
| Source dataset | uspto-grants-1978_03 |
| ORD ID | ord-00aa0f10b9634c7eaa8c51c72610ed0d |
| Source note | uspto-grants-1978_03 |