Ammonia → HCID 22382702, compound

HRID 1679613Notes

Reaction equation

HRID 1679613 reaction equation
[CH:1]12[CH2:9][CH:5]([C:6]1([CH3:8])[CH3:7])[CH2:4][CH:3]([C:10](Cl)=[O:11])[CH:2]2[CH3:13].[NH3:14]>>[CH:1]12[CH2:9][CH:5]([C:6]1([CH3:8])[CH3:7])[CH2:4][CH:3]([C:10]([NH2:14])=[O:11])[CH:2]2[CH3:13]

Participants

3

Reactant 2

HCID 222AmmoniaHCID 54233952HCID 54233952, compound

Product 1

HCID 22382702HCID 22382702, compound

Procedure

2g of (+)-pinane-3-carboxylic acid chloride are mixed with concentrated aqueous ammonia solution; the corresponding carboxylic acid amide precipitates and is filtered off and dried. It melts at 131° C and has an optical rotation of [α]D24 = +22.4° (c = 1, methanol).

Workup

  1. customthe corresponding carboxylic acid amide precipitates
  2. filtrationis filtered off
  3. customdried

Sources & evidence

ORD record
ord-7db17dd558db4a26b8353520b5ee7dba
Source dataset
uspto-grants-1978_03
Patent number
US04081477

Reaction notes

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