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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 167963Generated: October 30, 2026

Tetrahydrofuran → (3-{6-Amino-5-[1-(2,6-dichloro-3-fluoro-phenyl)-ethoxy]-pyridin-3-yl)-prop-2-ynyl)-carbamic acid tert-butyl ester

https://huagongshe.com/reaction/167963

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
Reactanttert-butyl N-(prop-2-yn-1-yl)carbamateHCID 11073648—
Reactant3-[1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-iodopyridin-2-amineHCID 21111395—
ReactantHCID 178420554HCID 178420554—
Product(3-{6-Amino-5-[1-(2,6-dichloro-3-fluoro-phenyl)-ethoxy]-pyridin-3-yl)-prop-2-ynyl)-carbamic acid tert-butyl esterHCID 58885785—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-59528944d1dd4232baf86eb7e5578c38
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)