HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dicyclohexylcarbodiimide → 5,5-Dimethyl-8-(4-fluorophenyl-1-methylbutyl)-2-(2-propynyl)-1,2,3,4-tetrahydro-10-[4-(thiomorpholino)butyryloxy]-5H[1] benzopyrano[3,4-d]pyridine hydrobromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | 5,5dimethyl-10-hydroxy-8-(4-fluorophenyl-1-methylbutyl)-2(2-propynyl)-1,2,3,4-tetrahydro-5H[1]benzopyrano[3,4-d]pyridine | HCID 53819439 | — |
| Reactant | gamma-Thiomorpholinobutyric acid hydrobromide | HCID 70564642 | — |
| Product | 5,5-Dimethyl-8-(4-fluorophenyl-1-methylbutyl)-2-(2-propynyl)-1,2,3,4-tetrahydro-10-[4-(thiomorpholino)butyryloxy]-5H[1] benzopyrano[3,4-d]pyridine hydrobromide | HCID 88808577 | — |
Reaction Steps
Equimolar amounts of 5,5dimethyl-10-hydroxy-8-(4-fluorophenyl-1-methylbutyl)-2(2-propynyl)-1,2,3,4-tetrahydro-5H[1]benzopyrano[3,4-d]pyridine, γ-thiomorpholinobutyric acid hydrobromide and dicyclohexylcarbodiimide are reacted to form the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04081449 |
| Source dataset | uspto-grants-1978_03 |
| ORD ID | ord-9fbf89251a7d4c599d6c911459181012 |
| Source note | uspto-grants-1978_03 |