HRID1679657

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID10868

Dicyclohexylcarbodiimide

C13H22N2

HCID14855682

4-(Pyrrolidin-1-yl)butanoic acid--hydrogen chloride (1/1)

C8H16ClNO2

结构：CCCC1(CCC)Oc2cc(CCCCCCCc3cccc(C)c3C)cc(O)c2C2=C1CCN(CC=Cc1ccccc1)C2

HCID54169433

未命名化合物

PRODUCTS

生成物

结构：CCCC1(CCC)Oc2cc(CCCCCCCc3cccc(C)c3C)cc(OC(=O)CCCN3CCCC3)c2C2=C1CCN(CC=Cc1ccccc1)C2.Cl

HCID70624259

未命名化合物

PROCEDURE

实验过程

2-Cinnamyl-8-(2,3-dimethylphenyl-n-heptyl)-5,5-di(n-propyl)-10-hydroxy-1,2,3,4-tetrahydro-5H[1]benzopyrano [3,4-d]pyridine, γ-pyrrolidinobutyric acid hydrochloride and dicyclohexylcarbodiimide are reacted in equimolar amounts according to Example 1 to form the desired product.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8c2431d9d2314b0e923d813856f28324
来源数据集: uspto-grants-1978_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04081449
来源说明: uspto-grants-1978_03

反应 SMILES

[CH2:1]([N:10]1[CH2:15][C:14]2[C:16]3[C:29]([OH:30])=[CH:28][C:27]([CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][C:38]4[CH:43]=[CH:42][CH:41]=[C:40]([CH3:44])[C:39]=4[CH3:45])=[CH:26][C:17]=3[O:18][C:19]([CH2:23][CH2:24][CH3:25])([CH2:20][CH2:21][CH3:22])[C:13]=2[CH2:12][CH2:11]1)[CH:2]=[CH:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[ClH:46].[N:47]1([CH2:52][CH2:53][CH2:54][C:55](O)=[O:56])[CH2:51][CH2:50][CH2:49][CH2:48]1.C1(N=C=NC2CCCCC2)CCCCC1>>[ClH:46].[CH2:1]([N:10]1[CH2:15][C:14]2[C:16]3[C:29]([O:30][C:55](=[O:56])[CH2:54][CH2:53][CH2:52][N:47]4[CH2:51][CH2:50][CH2:49][CH2:48]4)=[CH:28][C:27]([CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][C:38]4[CH:43]=[CH:42][CH:41]=[C:40]([CH3:44])[C:39]=4[CH3:45])=[CH:26][C:17]=3[O:18][C:19]([CH2:23][CH2:24][CH3:25])([CH2:20][CH2:21][CH3:22])[C:13]=2[CH2:12][CH2:11]1)[CH:2]=[CH:3][C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=1