HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 20361842, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Borane | HCID 6331 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 20361845 | HCID 20361845 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 20361842 | HCID 20361842 | — |
Reaction Steps
Add 150 ml. of a 1M solution of borane in tetrahydrofuran to 15.0 g. (0.038 mole) of 5-chloro-7-iodo-3-phenylbenzo[b]furan-2-carboxamide in 130 ml. of tetrahydrofuran and boil under reflux for 16 hours. Treat the solution with 8 ml. of 5% hydrochloric acid and reflux for 45 minutes more. Cool and make basic with sodium hydroxide solution.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04081549 |
| Source dataset | uspto-grants-1978_03 |
| ORD ID | ord-0049f209c1b74099809e4d55afa8f810 |
| Source note | uspto-grants-1978_03 |