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HRID1679687

反应详情

EQUATION

反应方程式

HRID 1679687 的结构方程式

REACTANTS

反应物

2
结构：C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2[C@@H](O)C[C@]2(C=O)[C@@H](C(=O)CO)CC[C@@H]12
HCID5839

Aldosterone

C21H28O5

结构：C=C[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3CC[C@]12C
HCID13034987

未命名化合物

PRODUCTS

生成物

1
结构：C[C@]12CCC(=O)C=C1CC[C@@H]1[C@@H]2[C@@H](O)C[C@]2(CO)[C@@H](C(=O)CO)CC[C@@H]12
HCID11222

18-Hydroxycorticosterone

C21H30O5

PROCEDURE

实验过程

Commercially available 1,4-pregnendiene-3-one was incubated with aldosterone-producing adrenal tissue and Δ1 18-hydroxycorticosterone isolated chromatographically. The diol was then converted to the 11β,18-oxido derivative by refluxing for 30 minutes in ethylene dichloride containing p-toluenesulfonic acid in the same manner described in connection with Example 1 above.