Pyridine → HCID 86735579, compound

HRID 1679691Notes

Reaction equation

HRID 1679691 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:9](=O)[CH2:10][CH2:11][CH2:12][CH2:13][O:14][CH3:15])[CH:5]=[CH:6][C:7]=1[Cl:8].Cl.Cl.[NH2:19][O:20][CH2:21][CH2:22][NH2:23].N1C=CC=CC=1>C(O)C>[ClH:1].[NH2:23][CH2:22][CH2:21][O:20][N:19]=[C:9]([C:4]1[CH:5]=[CH:6][C:7]([Cl:8])=[C:2]([Cl:1])[CH:3]=1)[CH2:10][CH2:11][CH2:12][CH2:13][O:14][CH3:15]

Participants

5

Reactant 3

HCID 1049PyridineHCID 143623262-(O-aminooxy)ethylamine dihydrochlorideHCID 584368751-(3,4-Dichlorophenyl)-5-methoxypentan-1-one

Product 1

HCID 86735579HCID 86735579, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 14 mmol (3.65 g) of 3', 4'-dichloro-5-methoxyvalerophenone, 14 mmol (2.1 g) of 2-aminooxyethylamine dihydrochloride, 7 ml of pyridine and 14 ml of absolute ethanol was refluxed for 2 hours. The reaction mixture was then further processes as described in Example 4. After crystallization from a mixture of ether and petroleum ether (boiling point 40°-60° C) the above entitled compound was obtained with a melting point of 93°-94° C.

Workup

  1. temperaturewas refluxed for 2 hours
  2. customAfter crystallization
  3. additionfrom a mixture of ether and petroleum ether (boiling point 40°-60° C) the above entitled compound
  4. customwas obtained with a melting point of 93°-94° C.

Sources & evidence

ORD record
ord-26628989d15844feb9bf5cf70a328520
Source dataset
uspto-grants-1978_03
Patent number
US04081552

Reaction notes

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