Water → HCID 13281225, compound

Participants

Reaction Steps

To benzhydryl 3-chloro-7-phenylacetamido-3-cephem-4-carboxylate (1.038 g) in a mixture of acetic acid (30 ml) and methylene chloride (10 ml) one adds activated zinc powder (3.9 g), stirs at room temperature for 1 hour, filters, dilutes with water, extracts with methylene chloride, washes with water, dries, concentrates, and crystallizes from ether to give benzhydryl 7-phenylacetamido-3-cephem-4-carboxylate (865 mg), m.p. 168°-170° C.

Provenance & Evidence