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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1679737Generated: October 25, 2026

2,3-Dichlorothioanisole → 2',3'-Dichloro-4'-methylthio-2-cyclopentylacetophenone

https://huagongshe.com/reaction/1679737

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-DichlorothioanisoleHCID 2758224—
ReactantCyclopentylacetyl chlorideHCID 3485182—
ReactantAluminum(III) ChlorideHCID 6451240—
SolventDichloromethaneHCID 6344—
Product2',3'-Dichloro-4'-methylthio-2-cyclopentylacetophenoneHCID 20358446—

Reaction Steps

2',3'-Dichloro-4'-methylthio-2-cyclopentylacetophenone is prepared following substantially the same procedure described in Example 10, Step A, using the following substances: 2,3-dichlorothioanisole (63.1 g., 0.327 mole), methylene chloride (300 ml.), cyclopentylacetyl chloride (52.7 g., 0.367 mole) and aluminum chloride (48.0 g., 0.36 mole).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04081554
Source datasetuspto-grants-1978_03
ORD IDord-e7cf466d639f45cba72702bb8087931f
Source noteuspto-grants-1978_03