Pyridinium chloride → HCID 12395666, compound

HRID 1679742Notes

Reaction equation

HRID 1679742 reaction equation
[CH3:1][C:2]1([CH3:22])[CH:10]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:9]2[C:4](=[C:5]([Cl:20])[C:6]([Cl:19])=[C:7]([O:17]C)[CH:8]=2)[C:3]1=[O:21].Cl.N1C=CC=CC=1>O>[CH3:1][C:2]1([CH3:22])[CH:10]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[C:9]2[C:4](=[C:5]([Cl:20])[C:6]([Cl:19])=[C:7]([OH:17])[CH:8]=2)[C:3]1=[O:21]

Participants

4

Reactant 2

HCID 10176127Pyridinium chlorideHCID 12395658HCID 12395658, compound

Product 1

HCID 12395666HCID 12395666, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
180 °C

Procedure

A stirred mixture of 2,2-dimethyl-3-phenyl-5-methoxy-6,7-dichloro-1-indanone (6.5 g., 0.02 mole) and pyridine hydrochloride (60 g.) is heated at 180° C. for 2 hours, then poured into water (800 ml.). The 2,2-dimethyl-3-phenyl-5-hydroxy-6,7-dichloro-1-indanone which separate (5.10 g.) melts at 259°-262° C. after recrystallization from ethanol water, 2:1.

Workup

  1. customThe 2,2-dimethyl-3-phenyl-5-hydroxy-6,7-dichloro-1-indanone which separate (5.10 g.) melts at 259°-262° C.
  2. customafter recrystallization from ethanol water, 2:1

Sources & evidence

ORD record
ord-06dc8cbeeaa24311a114cdf4b7f618b8
Source dataset
uspto-grants-1978_03
Patent number
US04081554

Reaction notes

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