HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Dichloroaniline → 2(3-trifluoromethylphenoxy)N-(3,4-dichlorophenyl)nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Dichloroaniline | HCID 7257 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-(3-Trifluoromethylphenoxy)nicotinoyl chloride | HCID 11162424 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 2(3-trifluoromethylphenoxy)N-(3,4-dichlorophenyl)nicotinamide | HCID 12852220 | — |
Reaction Steps
In the manner as in Example 1, 2.75 grams (0.009 mole) of 2(3-trifluoromethylphenoxy)nicotinoyl chloride, 1.5 grams (0.009 mole) 3,4-dichloroaniline, 0.9 grams (0.009 mole) triethylamine and 125 milliliters toluene were combined to yield 2.3 grams (59.8% of theoretical yield) of the desired product, a waxy solid. The structure was confirmed by mass spectrometry.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04270946 |
| Source dataset | uspto-grants-1981_06 |
| ORD ID | ord-2579757cab574dd38f3afabdd24a188e |
| Source note | uspto-grants-1981_06 |