HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetoacetate → HCID 23458160, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetoacetate | HCID 8868 | — |
| Reactant | HCID 54477569 | HCID 54477569 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | p-Toluenesulfonic acid | HCID 6101 | — |
| Catalyst | Platinum | HCID 23939 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 23458160 | HCID 23458160 | 73.9% |
Reaction Steps
A mixture of 18.0 g (0.1 mole) of m-nitroacetamido aniline, 26.0 g (0.2 mole) ethyl acetoacetate, 100 ml ethanol, 3.0 g of 5% Pt/C and 0.5 g of p-toluenesulfonic acid is treated in an autoclave at 165° C. and 1,000 psi of hydrogen until the uptake of hydrogen ceases. The solvent and catalyst are removed to yield 19.53 g of ethyl 3-(3'-acetamidophenylamino)butyrate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04271071 |
| Source dataset | uspto-grants-1981_06 |
| ORD ID | ord-7d3959c0fe54458daf0c44bc734673d1 |
| Source note | uspto-grants-1981_06 |