Carbamimidic acid, methyl ester, sulfate (1:1) → Guanidinium sulphate

HRID 1680049Notes

Reaction equation

HRID 1680049 reaction equation
C(N(CCCCCCCC)CCC[NH:13][C:14]([NH2:16])=[NH:15])CCCCCCC.[S:25]([OH:29])([OH:28])(=[O:27])=[O:26].COC(=N)N>>[S:25]([O-:29])([O-:28])(=[O:27])=[O:26].[NH2:15][C:14]([NH2:16])=[NH2+:13].[NH2:15][C:14]([NH2:16])=[NH2+:13]

Participants

3

Reactant 2

HCID 169039Carbamimidic acid, methyl ester, sulfate (1:1)HCID 178443616HCID 178443616, compound

Product 1

HCID 129653717Guanidinium sulphate

Procedure

Using the procedure of Process I, 590 g (2 moles) of 1-dioctylamino-3-guanidino-propane are reacted with 236 g (0.96 moles) of O-methylisourea sulfate. After working up the reaction batch, 651 g (83.7% of the theoretical yield) of guanidinium sulfate are obtained.

Sources & evidence

ORD record
ord-31b41e0fe55145f7b41381006e69ec24
Source dataset
uspto-grants-1981_06
Patent number
US04271190

Reaction notes

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