HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1680055Generated: November 1, 2026
Dicyclohexylcarbodiimide → HCID 131712257, compound
https://huagongshe.com/reaction/1680055
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | 5-tert-Butyl N-((phenylmethoxy)carbonyl)-L-glutamate | HCID 107472 | — |
| Reactant | HCID 131712258 | HCID 131712258 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 131712257 | HCID 131712257 | — |
Reaction Steps
843 mg Z-Glu(OtBU)-OH and 676 mg HOBt are dissolved in 10 ml DMF. After cooling to -22° C., 2.82 g H-Lys(Boc)-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-OtBu (Example VII.2) and 517 mg DCCI, dissolved in 2 ml DMF, are added to the solution. After stirring at -22° C. for some time, the DCHU is filtered out and the filtrate is evaporated to dryness.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04271152 |
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| Source dataset | uspto-grants-1981_06 |
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| ORD ID | ord-fb7aa888e3624fb4bfcc6f83480217c2 |
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| Source note | uspto-grants-1981_06 |
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