HCID 23459080, compound → HCID 23459081, compound

HRID 1680077Notes

Reaction equation

HRID 1680077 reaction equation
[C:1]1([CH:7]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[O:8][C:9]2[CH:14]=[CH:13][N+:12]([O-])=[CH:11][CH:10]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>C(O)C.[Ni]>[C:16]1([CH:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[O:8][C:9]2[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=2)[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1

Participants

4

Reactant 1

HCID 23459080HCID 23459080, compound

Product 1

HCID 23459081HCID 23459081, compoundYield 64.7%

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 702EthanolSolvent

Procedure

4-Diphenylmethoxypyridine-1-oxide (5.0 g; 0.018 m) was hydrogenated in ethanol (100 ml) at a pressure of 2 atmospheres using 5 g, of freshly alcohol washed Crosfield Raney nickel. After two hours at room temperature the mixture was filtered, and the solvent removed, leaving an oil that crystallised from petrol (60-80) to give 3.05 g of 4-diphenylmethoxypyridine as white crystals, m.pt. 68°-70° C.

Workup

  1. filtrationAfter two hours at room temperature the mixture was filtered
  2. customthe solvent removed
  3. customleaving an oil that
  4. customcrystallised from petrol (60-80)

Sources & evidence

ORD record
ord-0404556754bd4bcca581e945b30f6cfb
Source dataset
uspto-grants-1981_06
Patent number
US04271304

Reaction notes

Loading…