HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1680079Generated: October 31, 2026
L 1215 → N-[5-(3-fluoromethoxyphenyl)-1,3,4-thiadiazol-2-yl]-2,6-dimethoxybenzamide
https://huagongshe.com/reaction/1680079
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | L 1215 | HCID 129684 | — |
| Reactant | HCID 1451418 | HCID 1451418 | — |
| Reactant | HCID 8414150 | HCID 8414150 | — |
| Reactant | HCID 12881502 | HCID 12881502 | — |
| Reactant | HCID 12881505 | HCID 12881505 | — |
| Reactant | HCID 12881506 | HCID 12881506 | — |
| Reactant | HCID 12881507 | HCID 12881507 | — |
| Reactant | HCID 12881523 | HCID 12881523 | — |
| Reactant | N-[5-(5-chloro-2-benzo[b]furyl)-1,3,4-thiadiazol-2-yl]-2,6-dimethoxybenzamide | HCID 12881526 | — |
| Reactant | N-[5-(2-benzo[b]furyl)-1,3,4-thiadiazol-2-yl]-2,6-dimethoxybenzamide | HCID 12881528 | — |
| Reactant | HCID 12881532 | HCID 12881532 | — |
| Reactant | HCID 12881534 | HCID 12881534 | — |
| Reactant | HCID 12881535 | HCID 12881535 | — |
| Product | N-[5-(3-fluoromethoxyphenyl)-1,3,4-thiadiazol-2-yl]-2,6-dimethoxybenzamide | HCID 23458597 | — |
Reaction Steps
The preferred compounds of this invention are N-[5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl]-2,6-dimethylbenzamide, N-[5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl]-2,6-dimethoxybenzamide, N-[5-(4-fluorophenyl)-1,3,4-thiadiazol-2-yl]-2,6-dimethylbenzamide, N-[5-(4-trifluoromethylphenyl)-1,3,4-thiadiazol-2-yl]-2,6-dimethylbenzamide, N-[5-(4-fluorophenyl)-1,3,4-thiadiazol-2-yl]-2,6-dimethoxybenzamide, N-[5-(3-trifluoromethylphenyl)-1,3,4-thiadiazol-2-yl]-2,6-dimethoxybenzamide, N-[5-(2-benzo[b]furyl)-1,3,4-thiadiazol-2-yl]-2,6-dimethoxybenzamide, N-[5-(3-chlorophenyl)-1,3,4-thiadiazol-2-yl]-2,6-dimethoxybenzamide, N-[5-[3,5-bis(trifluoromethyl)phenyl]-1,3,4-thiadiazol-2-yl]-2,6-dimethoxybenzamide, N-[5-(4-trifluoromethylphenyl)-1,3,4-thiadiazol-2-yl]-2,6-dimethoxybenzamide, N-[5-(5-fluoro-2-benzo[b]furyl)-1,3,4-thiadiazol-2-yl]-2,6-dimethoxybenzamide, N-[5-(5-chloro-2-benzo[b]furyl)-1,3,4-thiadiazol-2-yl]-2,6-dimethoxybenzamide and N-[5-(4-pentafluoroethoxyphenyl)-1,3,4-thiadiazol-2-yl]-2,6-dimethoxybenzamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04271166 |
|---|
| Source dataset | uspto-grants-1981_06 |
|---|
| ORD ID | ord-9592629ff61742829e31df4981f04cab |
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| Source note | uspto-grants-1981_06 |
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