HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → N-methyl-2-(4-chlorophenyl)-3-methylbutyramide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | Benzeneacetic acid, 4-chloro-alpha-(1-methylethyl)- | HCID 16197 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Product | N-methyl-2-(4-chlorophenyl)-3-methylbutyramide | HCID 20571388 | — |
Reaction Steps
Following the methods of Example 1, 2-(4-chlorophenyl)-3-methylbutanoic acid is reacted with oxalyl chloride and aqueous methylamine to give N-methyl-2-(4-chlorophenyl)-3-methylbutyramide, which is then combined with 3-phenoxybenzyl bromide and AgBF4, yielding 3-phenoxybenzyl N-methyl-2-(4-chlorophenyl)-3-methylbutanimidate, MS m/e 407 (M+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04272449 |
| Source dataset | uspto-grants-1981_06 |
| ORD ID | ord-58331bc3d7554a0e99f91d087f8a5456 |
| Source note | uspto-grants-1981_06 |