HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → HCID 70573760, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | tert-Butanol | HCID 6386 | — |
| Reactant | 4-(2,6-Dichloroanilino)-3-thiophenacetic acid methyl ester | HCID 57145236 | — |
| Product | HCID 70573760 | HCID 70573760 | — |
Reaction Steps
316 mg (1 mmole) of 4-(2,6-dichloroanilino)-3-thiophenacetic acid methyl ester are warmed to 60° in 20 ml of tert.-butanol and 2 ml of concentrated sulfuric acid for 2 hours. The excess alcohol is distilled off. Chromatography on a column (silica gel/methylene chloride) gives, in the first fraction, 4-(2,6-dichloroanilino)-3-thiophenacetic acid tert.-butyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04272507 |
| Source dataset | uspto-grants-1981_06 |
| ORD ID | ord-00c18c7984be48b1a93d666f42ff57cd |
| Source note | uspto-grants-1981_06 |